When Your Body Ignores Its Own Stop Signs: The Leptin Resistance Paradox

When Your Body Ignores Its Own Stop Signs: The Leptin Resistance Paradox ~ What if I told you that your body has an elegant messaging system that should prevent obesity, yet somehow 42% of American adults remain obese? The hormone leptin—our built-in satiety signal—works perfectly in theory, telling our brains when we’ve had enough food. But in reality, many people’s brains have become deaf to these crucial messages, creating a physiological paradox where fuller fat cells produce more leptin, yet the brain behaves as if it’s starving. This communication breakdown might be the key to understanding why diets so often fail. ...

July 3, 2025 · 9 min